FOXO4-DRI Peptide 10mg Lyophilized Powder

FOXO4-DRI is a synthetic modified peptide developed for laboratory research involving FOXO4–p53 protein interaction, cellular senescence, and stress-response signaling. It is designed as a D-retro-inverso peptide, a structure used to improve stability and resistance to proteolytic degradation in experimental systems.

In biochemical and cellular models, FOXO4-DRI has been used as a research tool to examine how disruption of the FOXO4–p53 axis affects senescent-cell signaling, transcription factor regulation, and pathway-specific stress responses. Research interest in this peptide is closely related to studies of aging biology, cell-cycle regulation, tissue homeostasis, and senescence-associated mechanisms.

ACDC supplies FOXO4-DRI peptide as a high-purity lyophilized powder in sealed research vials for laboratory use. More peptide materials are available through the official catalog:
https://acdcsource.com/

Product Information

Product Name: FOXO4-DRI
Synonyms: FOXO4 inhibitory peptide, FOXO4 decoy peptide
CAS Number: 2460055-10-9
Peptide Type: Synthetic modified peptide / protein–protein interaction inhibitor
Molecular Formula: C228H388N86O64
Molecular Weight: 5358.05 g/mol
Appearance: White to off-white lyophilized powder
Purity: ≥98% to 99% (HPLC)
Pack Size: 10mg per vial
Solubility: Soluble in water or buffered aqueous solutions
Storage: Store at –20°C, desiccated and protected from light

Additional research peptides and lyophilized peptide powders can be viewed at:
https://acdcsource.com/

Sequence Information

Sequence:
DLeu-DThr-DLeu-DArg-DLys-DGlu-DPro-DAla-DSer-DGlu-DIle-DAla-DGln-DSer-DIle-DLeu-DGlu-DAla-DTyr-DSer-DGln-DAsn-Gly-DTrp-DAla-DAsn-DArg-DArg-DSer-Gly-Gly-DLys-DArg-DPro-DPro-DPro-DArg-DArg-DArg-DGln-DArg-DArg-DLys-DLys-DArg-Gly

Research Context

FOXO4-DRI is commonly described in research as a peptide designed to interfere with the interaction between FOXO4 and p53 in senescent cells. In laboratory settings, this mechanism is used to investigate:

• FOXO4–p53 protein–protein interactions

• cellular senescence pathways

• stress-response signaling

• aging and cell-cycle biology

• senescence-associated secretory phenotype (SASP) models

Published experimental work has examined FOXO4-DRI in models related to aging, tissue homeostasis, stress-induced senescence, and pathway-specific regulation of senescent-cell survival.

Handling and Storage

For laboratory use, FOXO4-DRI should be handled under clean, dry conditions.

Recommended handling procedures include:

• Reconstitute in sterile water or an appropriate buffered solution

• Avoid vigorous agitation during dissolution

• Aliquot reconstituted solutions to minimize repeated freeze–thaw cycles

• Store reconstituted material at –20°C or below for long-term stability

• Protect the lyophilized material from light, moisture, and excessive heat

These procedures help maintain peptide stability during experimental use.

Quality and Supply

ACDC supplies FOXO4-DRI peptide with:

• high-purity HPLC verification

• batch-specific COA documentation

• sealed vial packaging

• stable transport packaging

• OEM packaging support where required

ACDC research peptide materials are intended for laboratory and analytical environments.
Browse more peptide products here:
https://acdcsource.com/

FAQ

What is FOXO4-DRI peptide?

FOXO4-DRI is a synthetic modified peptide used in laboratory research to study the interaction between FOXO4 and p53, especially in experimental models of cellular senescence.

What is FOXO4-DRI used for in research?

It is commonly used in studies involving cellular senescence, stress-response signaling, aging biology, and transcription factor regulation.

What form is FOXO4-DRI supplied in?

ACDC supplies FOXO4-DRI as lyophilized peptide powder in sealed research vials.

How should FOXO4-DRI be stored?

The peptide should be stored desiccated, protected from light, and kept at –20°C. Reconstituted solutions should be aliquoted to reduce repeated freeze–thaw cycles.

Is FOXO4-DRI intended for human or veterinary use?

No. FOXO4-DRI supplied by ACDC is intended strictly for laboratory research use only and is not for human or veterinary application.

Where can I find more research peptides from ACDC?

Additional peptide materials and research compounds are available at:
https://acdcsource.com/

Research Use Only

This product is supplied by ACDC strictly for laboratory research purposes only.
It is not intended for human consumption, veterinary use, or clinical application.