Products
AICAR (Acadesine) 50mg – In stock
Product Introduction:
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide), also known as Acadesine or AICA-Riboside, is an adenosine monophosphate (AMP) analogue widely used in metabolic and cellular energy research. As a nucleotide-related compound, AICAR is involved in pathways linked to energy regulation, cellular metabolism, and nucleotide biosynthesis.
In cellular systems, AICAR is phosphorylated to form ZMP, which activates AMP-activated protein kinase (AMPK), a key regulator of cellular energy homeostasis.
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Product Specifications
- Content: 5mg per vial
- Form: Lyophilized powder
- Purity: ≥98%
- Storage: 2–8°C (short-term), −20°C recommended for long-term
- Use: Laboratory research and analytical work only
Product Overview
Adipotide is a synthetic peptide construct composed of a targeting sequence linked to a proteolysis-resistant motif. The compound is structured as a disulfide-bridged cyclic peptide connected to a D-enantiomeric domain, designed for selective interaction in experimental models.
This peptide is commonly referenced in scientific studies focusing on adipose tissue biology, vascular targeting, and metabolic pathway investigation.
Research Rationale
Researchers explore adipotide in controlled settings to examine:
- Selective targeting of vasculature associated with white adipose tissue
- Changes in endothelial signaling, perfusion, and vascular tone
- Cellular stress pathways such as ER stress, mitochondrial dynamics, and autophagy
- Transcriptional responses including PPAR signaling and AMPK-related pathways
In broader experimental designs, investigators may also monitor systemic markers such as glucose, insulin, lipid profiles, and inflammatory cytokines to understand whole-system responses.
Mechanistic Interest
Adipotide has been described in literature as interacting with endothelial receptors associated with adipose tissue vasculature. Following binding, the internalized peptide domain can disrupt mitochondrial function, leading to targeted cellular responses within experimental models.
These effects are studied to better understand adipose tissue regulation and vascular biology under controlled laboratory conditions.
Selecting Research-Grade Material
When sourcing adipotide for laboratory work, key considerations include:
- Purity & Identity: Verified by HPLC and mass spectrometry
- Trace Profile: Residual solvents and counter-ion consistency
- Stability: Proper storage and minimized freeze–thaw cycles
ACDC provides batch-level quality standards to support reproducible experimental workflows.
Related Research Categories
For metabolic and peptide research, related compounds are often studied alongside adipotide:
- GLP-related receptor peptides
- Amylin pathway peptides
- Multi-target peptide constructs
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Important Notice
All products offered by ACDC are:
- For laboratory research use only
- Not intended for human consumption
- Not for medical, diagnostic, or clinical use
FAQ
What is Adipotide used for?
Adipotide is used in laboratory research to study adipose tissue biology, vascular targeting mechanisms, and metabolic signaling pathways.
Is Adipotide approved for human use?
No. Adipotide is not approved for clinical or therapeutic use and is supplied strictly for research purposes.
How should Adipotide be stored?
Store at 2–8°C for short-term use. For extended storage, keep at −20°C and avoid repeated freeze–thaw cycles.
What should be checked before use?
Researchers typically verify purity (HPLC), molecular identity (MS), and storage stability before experimental use.
Where can I buy research peptides?
You can browse high-quality research peptides directly at:
👉 https://acdcsource.com/
